Defiance's second action-packed season begins, the lives of the townspeople remain in turmoil as Nolan (Grant Bowler) searches for Irisa (Stephanie Leonidas), Amanda (Julie Benz) deals with a personal loss and Stahma (Jaime Murray) plots to take over Datak's criminal empire. Meanwhile, Earth Republic's control of Defiance brings changes with far-reaching consequences, including a scheming new mayor (James Murray) whose secret agendas push the town towards its breaking point.

Studying abroad in Romania, high schoolers Charley and Ed must stop a sexy vampire's chilling plan to bathe in the blood of a "new moon virgin" -- who happens to be Charley's ex-girlfriend. The guys enlist the help of a vampire-hunting TV show host.